Just a quick note in case anyone else runs into this problem...
After the upgrade to 10 we experienced degraded search performance on a template search, querying just one field, that caused query response times to go from less than two seconds on LF9 to over two minutes on LF10. After working with Laserfiche they found a workaround and search times are back to normal. Hope this saves someone else a few days of troubleshooting.