Hi Billy,
Yes, you can do that in the user attributes section of the Laserfiche Administration Console, specifically under the Everyone group. Basically, you add the SID of the user or group that it applies to (that can even be everyone), of the form:
Name: [Lockdown]UserName
Data: S-1-9-12246189-1740016701-1132536036-2638486445-37810062-896=SearchSettings,DocViewPanes,AnnotationStyle,QuickSearch,AdvancedImport
Note that 'UserName' doesn't impact anything specifically, but it's a way for you to easily see who this applies to.
You can pick one or all of the 5 setting types. Once set, all covered users will get their settings directly from the everyone group, ignoring their own settings.
More specific information can be found at https://support.laserfiche.com/ow.aspx?WebAccess/Settings_Lockdown.
(And my apologies Chris, I must have missed the initial post).