Hello Beau,

In respect to your case in "Save to Repository", yes the changes will be reflected. 

Here are a few scenarios

1) Say you are running a process, and it gets suspended due to the account within the profile getting a password update, rendering the current configuration invalid. Once you update the profile, you can also change the file path of where you want the file so save. Then you would go to Results > and retry the "save to repository" task. The form will now save in the new folder location with the new credentials.

2) Say you have in progress Forms still pending to be reviewed by users. You wanted to change the account/password, so long as you validate/save after making the changes, whatever you changed will also be reflected. 

I hope this addresses your question.

However do note that this does not apply as simply to tasks such as "User Tasks". You can refer to this post for details in regards to changing "User Tasks".