It's going to depend on your data and on more of the form than you've shown us.
Does that field ever wrap to multiple lines?
Are the values well-known or is it literally any street name?
Do street names ever have colons, commas, and/or ampersands?
Are there always 1, 2, or 3 street names?
Do they always use the pattern A & B when there's two streets and A, B & C when there's three streets?
Is the whitespace consistently a single space?
Given what you've shown us, I'd recommend using two patterns and processing it in two (or more) stages. But your needs may vary a lot based on answers to the questions above.
Stage 1: Get the street names
STREET NAME: ([^:\r\n]+)
What does this do?
It strips the STREET NAME: text and makes the next pattern easier to create and reason about.
Stage 2: Break up the street names into multiple values (use the All matches option)
\s*([^,&]+){1,}
What does this do?
\s* says "ignore any whitespace before the first word"
(...){1,} says "find one more of the pattern within the parentheses"
[^,&]+ says "find one or more characters that are NOT caret or ampersand"
This causes the regex engine to collect all letters up to a caret or ampersand and make that a capture group. Then, do that again, and if there's at least one non-caret, non-ampersand character, start a second capture group (until a comma or ampersand is reached). Keep repeating this until the end of the string.
