I ran my test and after uploading my PDF as a TIFF, and then exporting it as a PDF again all of my hyperlinks and bookmarks were lost. I don’t think we can apply a blanket statement that all PDFs should be saved as TIFFs. I think the creator of each PDF should decide if there are special properties such as bookmarks, hyperlinks, or other features that exist within the document that should be preserved.
On a side note, I’m still confused why TIFF is the file of choice? It appears I can perform functions such as redaction and “email pages” from PDF files in Laserfiche.