Assigning security this way could quickly get out of hand. Can you explain your use case a little more so that we can see if another solution would work better?

Though it doesn't follow best practices, you can probably accomplish something like you ask if these fields are present on the documents you are trying to set.

You could try a combination of dynamic fields (pulls data from a database and allows you to have one field dependent on the selection of another) to set up the dropdown lists, and a Workflow with a Find User activity followed by the Assign Rights activity to assign the rights based on the selections in the field.