All research and communication I can find now suggests their is not real performance limitation on Volume Size.
I looked at the limitations of 2^31 Pages (2 Trillion +)
It is really just a matter of convenience regarding managing the Volume for back up etc..
Reason I ask is I want to Encrypt my Volume without worrying about Encrypting new or adding a password to numerous Roll Over Volumes.
So I was thinking just one Physical Volume.
Any concerns, gotchas?